The effects of temperature and salinity on hatching of spotted seatrout (Cynoscion nebulosus) eggs were examined. Spotted seatrout embryos obtained from a single hormone-induced spawn were exposed to twenty-five combinations of temperature (20, 23, 26, 29, and 32 C) and salinity (5, 15, 25, 35, and 45 except 45 o/oo, which had no survival at any test temperature. Salinity, temperature, and their interaction significantly affected percent hatch and percent of unhatched embryos. Hatching success was significantly better in the 15 and 25 o/oo test salinities. Hatching was significantly poorer at the 20 C test temperature. The occurrance of unhatched embryos was significantly higher in the 5 o/oo test salinity. Results indicated successful spawning may be reduced significantly in hypersaline (> 45 o/oo) habitats.