Eurell JAHaensly WEJournal of fish diseases2010-02-152010-02-151981http://hdl.handle.net/1969.3/23123187-194Micropogon undulatus L. were sampled from Galveston Bay, Texas, and transported to the research laboratory. Groups of five fish were exposed to 5 and 10% dilutions of the water soluble fraction (WSF) of southern Louisiana crude oil for 1, 3, 7, 14 and 21 days. Selected histochemical parameters of liver sections from control and WSF-exposed fish were evaluated. Glycogen was reduced in amount while glucose-6-phosphate dehydrogenase, lipid and cholesterol were increased in liver sections of WSF-exposed fish. These observations support a hypothesis that exposure to petroleum hydrocarbons increases mixed-function oxidase activity. The alterations were more obvious in sections from fish exposed to the higher level of the WSF. The histochemical parameters appeared most altered in hepatocytes near afferent hepatic blood vessels. These hepatocytes were the first cells of the liver to contact the pollutantsAtlantic croakercrude oilD 04803 Pollution effectseffects onfishGalveston BayhistochemistryHydrocarbonHydrocarbonsLaboratoriesliverMicropogon undulatusoiloxidasepetroleumPetroleum hydrocarbonsPollutantspollution effectsQ1 01504 Effects on organismsTexasUSAwaterX 24155 BiochemistryJournal